Azetidine based ligands in boron catalyzed asymmetric Diels-Alder reactions
Starmans WAJ, Walgers RWA, Thijs L, de Gelder R, Smits JMM, Zwanenburg B
TETRAHEDRON 54 (19): 4991-5004 MAY 7 1998

Abstract:
The preparation of a new class of azetidine-based auxiliaries and their selectivity in the BBr3 catalyzed Diets-Alder reaction is described. The results are compared with a similar proline-derived ligand and a known prolinol auxiliary. Results show that selectivities are highly dependent on the dienophile and the substituent of the chiral auxiliary. (C) 1998 Elsevier Science Ltd. All rights reserved.